Fig. 7.

Significant enrichment of spliceosome components in CLL. A, Overexpressed proteins demonstrated significant enrichment of the components of the KEGG pathway “spliceosome” (n = 36, p = 1.3 × 10⁻²¹). This pathway is annotated with those proteins identified as significantly overexpressed (p < 0.05), with both substantial (Rs>0.3) and marginal (0.1<Rs<0.3) overexpression annotated using red and yellow stars, respectively. B, The differential expressions observed for all proteins and the individual log₂ (ratios) for each CLL sample, mapping to the KEGG “spliceosome” pathway.