Table 2.
Cohort characteristics by HPV status (n=120)
| HPV− (n=34) | HPV + (n=86) | ||
|---|---|---|---|
| Characteristic | Median (range) | Median (range) | ap-value |
|
| |||
| Age at Diagnosis in years | 58.5 (36-85) | 58.5 (37-82) | 0.775 |
|
| |||
| Median Follow Up Time (months) | 45 (10-82) | 39 (6-88) | 0.309 |
|
| |||
| Tobacco pack-years (range) | 30 (0-68) | 18 (0-160) | 0.075 |
|
| |||
| Characteristic | Frequency (%) | Frequency (%) | ap-value |
|
| |||
| Gender | |||
| Male | 25 (73.5) | 71 (82.6) | |
| Female | 9 (26.5) | 15 (17.4) | 0.265 |
|
| |||
| Tobacco Status | |||
| Never | 4 (11.8) | 22 (25.6) | |
| Former | 22 (64.7) | 44 (51.2) | |
| Current | 8 (23.5) | 20 (23.3) | 0.228 |
|
| |||
| Overall tumor stage | |||
| Stage II | 2 (5.9) | 4 (4.7) | |
| Stage III | 6 (17.6) | 11 (12.8) | |
| Stage IV | 26 (76.5) | 71 (82.6) | 0.744 |
|
| |||
| T-Stage | |||
| T1/T2 | 17 (50.0) | 50 (58.1) | |
| T3/T4 | 17 (50.0) | 36 (41.9) | 0.418 |
|
| |||
| N-Stage | |||
| N0/N1 | 11 (32.4) | 19 (22.1) | |
| N2/N3 | 23 (67.6) | 57 (77.9) | 0.242 |
|
| |||
| Grade (n=114) | n=33 | n=81 | |
| Well/Moderately differentiated | 23 (69.7) | 30 (37.0) | |
| Poorly differentiated | 10 (30.3) | 51 (63.0) | 0.002 |
HN head and neck, T clinical tumor stage, N clinical nodal stage
a
Wilcoxon Rank Sum test (or Kruskal-Wallis test) was used to examine differences for age and tobacco pack-years and Pearson Chi-square test was used to examine differences for categorical variables