Figure 8.

Inhibitory synaptic bursts are induced by controlled cortical impact (CCI). (A) Voltage‐clamp recording of spontaneous inhibitory burst discharge observed in a CCI animal with an epileptiform EEG. For inhibitory recording glutamate receptor antagonists (APV/DNQX or kynurenate) were applied. Note the burst is comprised of compound sIPSCs and resembles epileptiform discharges observed in epileptic animals. (B) Bar charts of average values of various burst properties for control (n = 9) or CCI (n = 16). *P < 0.05, **P < 0.01.