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. 2018 Apr;4(2):a002386. doi: 10.1101/mcs.a002386

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© 2018 Beird et al.; Published by Cold Spring Harbor Laboratory Press

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial License, which permits reuse and redistribution, except for commercial purposes, provided that the original author and source are credited.

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Figure 1. — Whole-exome profiling of concurrent well-differentiated (WD) and dedifferentiated (DD) liposarcomas. (A,B) Representative hematoxylin and eosin stains of liposarcomas used in this study: WD and DD. (C) Boxplots of the total numbers of somatic mutations called by MuTect when comparing tumors with their matched normal samples. Only fresh frozen cases of WD (left) and DD (right) liposarcomas were included here. A paired t-test comparing the somatic mutation burdens between WD and DD liposarcomas was not significant (P = 0.36). (D) Venn diagram example showing the number of somatic mutations in patient 3 (DWN3) as called by MuTect.