Table 2. SELDI-TOF MS biomarkers detected in HIV/HCV co-infection.

m/z (/1,000)	Fractions and chemistries	P value (F1 vs F3-4)	AUC for ROC Curve (fold F1/F3-4)	Mean signal intensity ± SE				P value
				F1 (n = 20)	F2 (n = 20)	F3 (n = 20)	F4 (n = 8)
2.2	F6 CM10	0.002	0.73(1.65)	6.45 ± 2.54	7.19 ± 2.68	9.05 ± 3.01	12.20±2.61	0.008
4.6	F3 IMAC30	0.006	0.31(-2.04)	4.05 ± 2.01	2.68 ± 1.64	2.44 ± 1.56	1.09±1.36	0.010
6.4	F3 H50	0.007	0.27(-2.14)	6.42 ± 3.05	3.75 ± 2.94	3.97 ± 2.45	1.61±1.62	0.002
8.1	F6 CM10	0.007	0.27(-0.58)	3.07 ± 1.83	2.97 ± 1.45	2.04 ± 1.06	1.51±1.01	0.006
8.9	F3 IMAC	0.005	0.31(-1.71)	1.82 ± 1.19	1.59 ± 1.13	1.23 ± 1.38	0.73±0.82	0.013
9.3	F6 H50, F3 IMAC30-CM10	0.002	0.29(-2.55)	11.33 ± 3.37	10.12 ± 3.18	5.84 ± 2.42	2.50±1.68	0.002
13.8	F6-F1 H50,	0.004	0.30(-1.33)	1.80 ± 0.54	1.39 ± 0.67	1.45 ± 0.33	1.14±0.46	0.004
18.4	F1 CM10	0.009	0.28(2.13)	0.29 ± 1.19	0.46 ± 1.00	0.11 ± 1.00	0.17±0.83	0.021
22.8	F6-F3 CM10	0.010	0.67(1.65)	0.60 ± 0.78	0.82 ± 0.91	0.74 ± 0.86	1.28±1.11	0.014
24.2	F1 CM10	0.018	0.71(1.74)	0.58 ± 0.76	0.85 ± 0.92	0.87 ± 0.93	1.13±0.85	0.071
33.3	F3 CM10-IMAC30	0.004	0.71(1.32)	3.21 ± 1.79	3.91 ± 1.98	4.21 ± 2.05	4.54±1.20	0.015
66.6	F3 IMAC30	0.003	0.71(1.16)	23.88 ± 4.89	24.60 ± 4.96	26.75 ± 5.17	29.25±1.92	0.002
78.8	F6 IMAC30	0.010	0.69(1.54)	0.45 ± 0.67	0.66 ± 0.81	0.61 ± 0.78	0.76±0.64	0.030
133.4	F3 IMAC30	0.006	0.71(1.14)	2.32 ± 1.52	2.38 ± 1.54	2.69 ± 1.64	2.67±0.74	0.015

Mass-over-charge (m/z) value, mean signal intensity, and area-under-curve (AUC) for selected individuals differentially expressed peptides/proteins between hepatic fibrosis 0–1 (F1), fibrosis 2 (F2), fibrosis 3 (F3) and ESLD or fibrosis 4 (F4) patients.