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. 2018 Mar 28;12:639–645. doi: 10.2147/DDDT.S160865

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© 2018 Liao et al. This work is published and licensed by Dove Medical Press Limited.

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Propranolol with radiation-induced genetic expression in gastric cancer xenografts.

Notes: Propranolol down-regulated the expression of NF-κB-regulated gene products in gastric tumor samples. Immunohistochemical analyses of COX-2, EGFR, NF-κB, and VEGF expression levels showed the inhibition of COX-2, EGFR, NF-κB, and VEGF by propranolol in combination with radiation. Positive staining is seen for the indicated biomarkers. Samples from mice from each group were analyzed.