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. 2018 Mar 28;11:637–647. doi: 10.2147/JPR.S147735

Table 4.

Multilevel model examining the influence of state anxiety and trait catastrophizing on the time course of IL-6 responses during the nonpainful session among participants with chronic pain

Fixed effects β SE t p-value
Step 1
Intercept 2.50 0.635 3.94 <0.001
Time 0.243 0.051 4.76 <0.001
Pain-magnification (PCS) 0.16 0.25 0.66 ns
Time × pain-magnification (PCS) −0.028 0.020 −1.40 ns
Step 2
Intercept 2.43 0.62 3.89 <0.001
Time 0.25 0.052 4.76 <0.001
Anxiety 0.0002 0.005 0.038 ns
Pain-magnification (PCS) 0.178 0.021 0.709 ns
Time × pain-magnification (PCS) −0.032 0.021 −1.54 ns

Notes: Time and anxiety are Level 1 variables centered within participants. Catastrophizing is a Level 2 variable centered at the grand mean. β, unstandardized regression coefficient.

Abbreviations: IL, interleukin; ns, nonsignificant; PCS, Pain Catastrophizing Scale; SE, standard error.