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. 2018 Mar 28;11:1707–1720. doi: 10.2147/OTT.S157440

Figure 5.

Figure 5

Figure 5

Knockdown of KIF18B suppresses tumor growth in vivo.

Notes: (A) Tumor nodules from mice injected with sh-KIF18B cells are significantly smaller than those from mice injected with NC cells. (B) sh-KIF18B tumors generated from both HeLa and Siha cell lines have less dense Ki-67 staining. Magnification ×40.(C) Compared with the NC group, the sh-KIF18B group showed reduced tumor sizes. (D) Compared with the NC group, the sh-KIF18B group showed reduced tumor weight. **P<0.01, ***P<0.001. Error bars indicate the SEM.

Abbreviations: shRNA, small hairpin RNA; NC, negative control.