Table 2.

Univariate and Multivariate Analyses for Clinicopathologic Factors Associated with DSS in the MD Anderson Cohort

Factor	5-yr DSS (%)	Univariate Analysis		Multivariate Analysis 1		Multivariate Analysis 2		Points Assigned
		HR	P	HR	P	HR	P
Pathologic T Stage
T1	98.9	Referent		Referent				0
T2	95.9	4.3	<.0001	2.5	.001			1
T3	95.5	4.3	.001	2.5	.04			1
Pathologic N Stage
N0	98.7	Referent		Referent				0
N1mic	98.9	0.4	.4	.4	0.3			0
N1	97.1	1.9	.03	1.4	0.3			0
N2	93.7	5.8	<.0001	4.6	<.0001			2
N3	79.5	16.2	<.0001	8.6	<.0001			3
Pathologic Stage
I (A and B)	99.1	Referent				Referent		0
IIA	98.0	2.8	.002			2.3	.01	1
IIB	95.6	4.8	<.0001			4.0	<.0001	2
IIIA	95.4	6.8	<.0001			7.2	<.0001	3
IIIC	79.5	26.6	<.0001			19.9	<.0001	4
ER Status
Pos	98.8	Referent		Referent		Referent		0
Neg	92.9	4.9	<.0001	2.5	.001	2.5	.001	1
PR Status
Pos	98.8	Referent		Referent		Referent
Neg	95.2	4.0	<.0001		NS		NS
HER2 Status
Pos	97.5	Referent		Referent		Referent		0
Neg	98.0	0.8	.5	2.2	.03	2.2	.04	1
Nuclear Grade		Referent		Referent		Referent
1	99.8	5.0		4.2		4.0		0
2	98.9	25.0	.1	13.8	.2	13.0	.2	0
3	95.3		.001		.01		.01	1

Abbreviations: DSS, disease-specific survival; ER, estrogen receptor; PR, progesterone receptor