Table 2. Changes in body fat, body weight and waist circumference after 26 weeks on NND and ADD among high P/B and low P/B groups.
| High P/B group | Low P/B group | Pa | Pb | Pc | Pd | Δ(NND-ADD) in high P/B −Δ(NND-ADD) in low P/B | Pe | |||
|---|---|---|---|---|---|---|---|---|---|---|
| All subjects | NND (n=15) | ADD (n=13) | NND (n=21) | ADD (n=13) | ||||||
| ΔBody fat (kg) | −4.97 (−6.06; −3.88) | −1.82 (−3.01; −0.63) | −3.41 (−4.35; −2.48) | −2.53 (−3.69; −1.37) | <0.001 | 0.25 | 0.04 | 0.41 | −2.27 (−4.45; −0.09) | 0.041 |
| ΔWeight (kg) | −4.58 (−5.82; −3.34) | −1.09 (−2.43; 0.25) | −3.27 (−4.33; −2.22) | −2.11 (−3.43; −0.79) | <0.001 | 0.18 | 0.12 | 0.29 | −2.33 (−4.80; 0.15) | 0.065 |
| ΔWC (cm) | −5.19 (−6.99; −3.38) | −0.44 (−2.41; 1.52) | −3.09 (−4.64; −1.55) | −2.29 (−4.22; −0.37) | <0.001 | 0.53 | 0.09 | 0.19 | −3.95 (−7.55; −0.34) | 0.032 |
| Sensitivityf | NND (n=15) | ADD (n=13) | NND (n=16) | ADD (n=10) | ||||||
| ΔBody fat (kg) | −4.96 (−5.95; −3.97) | −1.79 (−2.87; −0.71) | −2.94 (−3.93; −1.94) | −2.71 (−3.92; −1.50) | <0.001 | 0.78 | 0.01 | 0.27 | −2.94 (−5.05; −0.85) | 0.006 |
| ΔWeight (kg) | −4.57 (−5.70; −3.45) | −1.07 (−2.29; 0.15) | −2.52 (−3.64; −1.40) | −2.56 (−3.93; −1.18) | <0.001 | 0.97 | 0.01 | 0.12 | −3.53 (−5.92; −1.15) | 0.004 |
| ΔWC (cm) | −5.14 (−6.91; −3.36) | −0.54 (−2.47; 1.39) | −2.29 (−4.07; −0.52) | −3.60 (−5.76; −1.43) | <0.001 | 0.36 | 0.03 | 0.04 | −5.90 (−9.65; −2.14) | 0.002 |
Abbreviations: ADD, Average Danish Diet; NND, New Nordic Diet; P/B, Prevotella-to-Bacteroides; WC, Waist circumference.
Data are presented as estimated mean body fat, body weight and waist circumference change from baseline and 95% confidence intervals for each combination of the diet-P/B strata interaction after 26 weeks in the linear mixed models, which were additionally adjusted for age, gender, baseline BMI, fasting glucose and insulin as well as random effects for subjects.
P-value representing the difference in dietary response within the high P/B group.
P-value representing the difference in dietary response within the low P/B group.
P-value representing the difference in response to NND between the P/B groups.
P-value representing the difference in response to ADD between the P/B groups.
P-value representing the following pairwise comparison using post hoc t-tests: Δ(NND-ADD) among subjects with high P/B−Δ(NND-ADD) among subjects with low P/B.
Sensitivity analyses excluding the eight subjects with Prevotella spp. below the detection limit.