Table 1. Anthropometric characteristics before, 6 weeks following meal-replacement and at the time of biopsy.
| ODR | ODS | |
|---|---|---|
| N | 10 | 10 |
| Before meal-replacement | ||
| Age (years) | 44±2 | 43±2 |
| Mass (kg) | 104.8±6.9 | 100.3±3.9 |
| BMI (kg m−2) | 37.7±2.0 | 37.8±1.1 |
| Following 6 weeks of 900 kcal diet | ||
| Mass (kg) | 98.0±6.5 | 88.6±3.4** |
| BMI (kg m−2) | 35.2±1.5 | 33.2±1.0** |
| % Weight loss | 6.5±0.2 | 11.7±0.2**** |
| At time of biopsy | ||
| Age (yr) | 48±2 | 52±2 |
| Mass (kg) | 100.9±7.3 | 93.2±5.9 |
| BMI (kg m−2) | 37.1±2.0 | 35.6±1.7 |
| Waist circumference (cm) | 113.9±4.7 | 112.1±4.2 |
| Body fat (%) | 49.8±1.8 | 47.4±1.2 |
| Fat mass (kg) | 46.7±4.1 | 42.5±3.1 |
| Lean mass (kg) | 45.4±2.3 | 46.9±3.1 |
| Respiratory quotient | 0.79±0.02 | 0.80±0.02 |
| VO2 (l min−1) | 0.23±0.01 | 0.23±0.01 |
| VCO2 (l min−1) | 0.18±0.01 | 0.18±0.01 |
| Resting metabolic rate (kcal day−1) | 1584±85 | 1604±86 |
| Physical activity (kcal) | 1222±216 | 1121±181 |
| TDEE (kcal day−1) | 3087±213 | 3004±216 |
| HOMA-IR | 9.2±1.9 | 13.1±2.9 |
**Two-way ANOVA, significantly different compared to before meal-replacement within group, P<0.01.
****P<0.0001 two-tailed unpaired t-test. Body fat distribution, P<0.05, two-tailed unpaired t-test.
Data are mean±s.e.m., n=10.