Table 4. Univariate analysis of factors associated with the effect of preoperative chemotherapy for advanced gastric cancer.
| Factors | Histopathology | P-value | ||
|---|---|---|---|---|
| grade 1b or over 29 | grade 0 or 1a 11 | |||
| Age | 70≧ | 9 | 2 | P = 0.416 |
| 70< | 20 | 9 | ||
| Sex | male | 25 | 6 | P = 0.032 |
| female | 4 | 5 | ||
| cT | T3(SS) | 6 | 1 | P = 0.544 |
| T4a(SE) | 22 | 10 | ||
| T4b(SI) | 1 | 0 | ||
| cN | N0 | 2 | 1 | P = 0.573 |
| N1 | 7 | 5 | ||
| N2 | 13 | 3 | ||
| N3 | 7 | 2 | ||
| cM | present | 17 | 9 | P = 0.170 |
| absent | 12 | 2 | ||
| cStage | IIB | 1 | 2 | P = 0.260 |
| IIIA | 6 | 4 | ||
| IIIB | 6 | 3 | ||
| IIIC | 4 | 0 | ||
| IV | 12 | 2 | ||
| Macroscopic | Type 2 | 10 | 4 | P = 0.417 |
| type | Type 3 | 11 | 2 | |
| Type 4 | 8 | 5 | ||
| Histological | differentiated | 9 | 2 | P = 0.416 |
| type | undifferentiated | 20 | 9 | |
| RPN2 | Negative | 20 | 1 | P = 0.001 |
| Positive | 9 | 10 | ||
| P-gp | Negative | 19 | 9 | P = 0.007 |
| Positive | 10 | 2 | ||
| ABCG2 | Negative | 21 | 6 | P = 0.281 |
| Positive | 8 | 5 | ||
| MRP1 | Negative | 16 | 6 | P = 0.972 |
| Positive | 13 | 5 | ||
Abbreviations: RPN2 = ribophorin II; P-gp = P-glycoprotein; ABCG2 = ATP-binding cassette sub-family G member 2; MRP1 = Multidrug resistance-associated Protein 1.
Analyzed by Fisher's exact test.