Table 2. Specificity of ddPCR assays.
PIK3CA H1047R | Copies/ml | |
---|---|---|
Mutant | Wild-type | |
OCCC13 Tumor tissue | 499 | 46,400 |
OCCC13 Normal tissue | 0 | 38,000 |
OCCC13 cfDNA | 165 | 63,300 |
Wild-type tissue (n=10) | 0 | 471,600 |
Normal cfDNA (n=3) | 0 | 108,800 |
Non-Template Control | 0 | 0 |
KRAS G12D | Copies/ml | |
Mutant | Wild-type | |
OCCC14 Tumor tissue | 13,300 | 21,500 |
OCCC14 Normal tissue | 0 | 52,800 |
OCCC14 cfDNA | 285 | 47,700 |
Wild-type tissue (n=10) | 0 | 532,200 |
Normal cfDNA (n=3) | 0 | 88,250 |
Non-Template Control | 0 | 0 |