Table 1. Baseline characteristic of studies included in the systematic review and meta-analysis.
Study | Country | Type of transplant | Mean or median age (yr) | Sample size | Number of renal transplant cases | Number of all cancers | Reported outcomes | Follow-up duration (yr) | NOS score |
---|---|---|---|---|---|---|---|---|---|
Hoshida 1997 [8] | Japan | Renal | 40.0 | 1744 | 1744 | 45 | All cancers, GC, HCC, BC, UC, UBC, RCC, TC | 7.4 | 8 |
Birkeland 2000 [9] | Denmark | Renal | 38.9 | 1821 | 1821 | 209 | All cancers, BC, UBC, RCC, Non-melanoma SC, LC, melanoma, TC, Hodgkin’s lymphoma, Non-Hodgkin lymphoma | 7.5 | 8 |
Kyllonen 2000 [10] | Finland | Renal | 41.5 | 2890 | 3440 | 230 | All cancers, BC, UBC, RCC, TC, CC, lymphoma, leukaemia, LC, Non-melanoma SC | 7.2 | 7 |
Vajdic 2006 [11] | Australia and New Zealand | Renal | 41.0 | 10180 | 10180 | 1236 | All cancers, BC, CC, HCC, LC, OC, PC, RCC, UBC, TC, UC, Hodgkin’s lymphoma, Non-Hodgkin lymphoma | 8.5 | 8 |
Vegso 2007 [12] | Hungary | Renal | 53.1 | 2535 | 2852 | 193 | All cancers, BC, lung cancer, Non-melanoma SC, PC, UBC, GC, RCC, melanoma, HCC, Non-Hodgkin’s lymphoma, TC | 9.8 | 7 |
Villeneuve 2007 [13] | Canada | Renal | NA | 11 155 | 11 391 | 778 | All cancers, LC, GC, CC, HCC, pancreatic cancer, lung cancer, BC, OC, UC, PC, RCC, UBC, TC, Hodgkin’s lymphoma, Non-Hodgkin lymphoma | 7.3 | 7 |
Collett 2010 [14] | UK | Multiorgan | NA | 25104 | 25104 | 4422 | All cancers, LC, GC, CC, HCC, pancreatic cancer, lung cancer, Non-melanoma SC, BC, OC, PC, RCC, UBC, TC, UC | NA | 8 |
Li 2012 [15] | China | Renal | 44.1 | 4716 | 4716 | 320 | All cancers, GC, CC, HCC, lung cancer, melanoma, Non-melanoma SC, OC, UBC, TC, UC | 4.8 | 7 |
Cheung 2012 [16] | China | Renal | 43.7 | 4674 | 4895 | 299 | All cancers, GC, CC, HCC, pancreatic cancer, lung cancer, melanoma, BC, OC, PC, RCC, UBC, TC, UC | 8.2 | 7 |
Krynitz 2013 [17] | Sweden | Multiorgan | NA | 7952 | 7952 | 2774 | All cancers, LC, GC, CC, HCC, pancreatic cancer, lung cancer, Non-melanoma SC, BC, OC, PC, RCC, UBC, TC, UC | 9.7 | 8 |
Piselli 2013 [18] | Italy | Renal | NA | 7217 | 7299 | 395 | All cancers, LC, GC, HCC, pancreatic cancer, lung cancer, melanoma, BC, OC, PC, RCC, UBC, TC, UC, Hodgkin’s lymphoma, | 5.5 | 8 |
*GC: gastric cancer; HCC: hepatocellular carcinoma; BC: breast cancer; UC: uterine cancer; UBC: urinary bladder cancer; RCC: renal cell cancer; TC: thyroid cancer; SC: skin cancer; CC: colon cancer; LC: lip cancer; OC: ovarian cancer; PC: prostate cancer.