Table 1.

SLC26A4-linked variants comprising the CEVA haplotype

Variant	Chromosome 7q position (bp)*	Reference genotype	CEVA genotype	Minor allele frequency†	CADD score‡
rs17424561	106669858	G	A	0.049	3.9
rs79579403	106741374	T	C	0.048	2.9
rs17425867	106764419	T	A	0.048	11.7
rs117113959	106815154	T	C	0.047	0.1
rs17349280	106837681	G	A	0.047	2.2
rs117386523	106930234	C	T	0.047	13.5
rs80149210	106967931	A	G	0.047	1.6
rs199667576	106993159	T	–	0.046	5.9
rs9649298	107014419	A	G	0.046	13.7
rs117714350	107147622	T	C	0.035	7.8
rs199915614	107242636	T	–	0.035	21.6
rs150942317	107282469	A	C	0.035	10.4

^*Based on hg19.

^†From European populations in 1000 Genomes phase 3.

^‡CADD scaled C-scores for predicted deleteriousness. Larger scores are more strongly predictive of deleteriousness. CADD, Combined Annotation Dependent Depletion; CEVA, Caucasian enlargement of the vestibular aqueduct.