Table 2.
All patients n = 27 |
CMR‐based diagnosis of cardiac sarcoidosisa
n = 14 |
CMR‐based exclusion of cardiac sarcoidosis n = 13 |
P‐value | |
---|---|---|---|---|
CMR‐assessed cardiac functional parameters and dimensions | ||||
LVEF (%) | 58.8 ± 10.3 | 57.0 ± 11.4 | 60.7 ± 9.0 | 0.36 |
LVEDV (mL) | 141.8 ± 48.5 | 150.1 ± 59.2 | 132.9 ± 33.6 | 0.37 |
IVSD (mm) | 9.8 ± 1.6 | 9.5 ± 1.4 | 10.3 ± 1.7 | 0.20 |
CMR‐assessed pathology's activity, n (%) | ||||
Only non‐viable tissue damage, as assessed by late gadolinium enhancement | 7 (50.0%) | |||
Both acute inflammatory and non‐viable tissue damage, as assessed by early relative gadolinium enhancement, T2 imaging, and late gadolinium enhancement | 6 (42.9%) | |||
Only acute inflammatory tissue damage, as assessed by early relative gadolinium enhancement | 1 (7.1%) | |||
CMR‐assessed localization of LGE according to AHA's segmentation and nomenclature,19 n (%) | ||||
1 basal anterior | 3 (8.3%) | |||
2 basal anteroseptal | 3 (8.3%) | |||
3 basal inferoseptal | 3 (8.3%) | |||
4 basal inferior | 2 (5.6%) | |||
5 basal inferolateral | 3 (8.3%) | |||
6 basal anterolateral | 2 (5.6%) | |||
7 mid‐anterior | 4 (11.1%) | |||
8 mid‐anteroseptal | 4 (11.1%) | |||
9 mid‐inferoseptal | 5 (13.9%) | |||
10 mid‐inferior | 0 (0.0%) | |||
11 mid‐inferolateral | 2 (5.6%) | |||
12 mid‐anterolateral | 4 (11.1%) | |||
13 apical anterior | 1 (2.8%) | |||
14 apical septal | 0 (0.0%) | |||
15 apical inferior | 0 (0.0%) | |||
16 apical lateral | 0 (0.0%) | |||
17 apex | 0 (0.0%) |
Data are presented as mean ± SD or total number and percentage (in parentheses), as appropriate.
AHA, American Heart Association; CMR, cardiovascular magnetic resonance; IVSD, diastolic interventricular septal thickness; LGE, late gadolinium enhancement; LVEDV, left ventricular end‐diastolic volume; LVEF, left ventricular ejection fraction.
Detection of cardiac sarcoidosis relied on presence of LGE; in case of early relative gadolinium enhancement or pathological T2‐weighted imaging, cardiac sarcoid involvement was suspected.