Table 1.

Trial inclusion and exclusion criteria

Inclusion criteria

Clinical diagnosis of acute decompensated heart failure (based on the European Society of Cardiology guidelines), regardless of left ventricular ejection fraction

Iron deficiency defined as serum ferritin <300 ng/mL if transferrin saturation is <20%

Able to complete the 6‐min walk test

Age 21 years and above

Exclusion criteria

Haemoglobin level above 14 g/dL

Known sensitivity to ferric carboxymaltose

Intravenous iron therapy or blood transfusion within 4 weeks prior to randomization

Body weight ≤35 kg

Iron storage disorders (e.g. haemochromatosis)

Serious medical conditions deemed prohibitive to study participation or completion by the investigators