Table 5.
Change in haematological and iron biomarkers
| FCM | Saline | P‐value | ||
|---|---|---|---|---|
| Ferritin ≥ 100 ng/mL (%) | Baseline | 10 (41.7) | 8 (32.0) | 0.56 |
| Weeks 4–6 | 20 (90.9) | 9 (39.1) | <0.0001 | |
| Week 12 | 19 (95.0) | 9 (39.1) | <0.0001 | |
| TSAT ≥ 20% (%) | Baseline | 8 (34.8) | 6 (24) | 0.53 |
| Weeks 4–6 | 16 (72.7) | 9 (39.1) | 0.04 | |
| Week 12 | 14 (70.0) | 11 (47.8) | 0.22 | |
| IDa (%) | Baseline | 15 (62.5) | 19 (76.0) | 0.48 |
| Weeks 4–6 | 3 (13.6) | 12 (52.2) | <0.0001 | |
| Week 12 | 4 (20.0) | 12 (52.2) | <0.0001 | |
| MCV (fL) | Baseline | 82 ± 7 | 84 ± 8 | 0.9 |
| Weeks 4–6 | 84 ± 6 | 84 ± 9 | 0.66 | |
| Week 12 | 85 ± 5 | 84 ± 9 | 0.13 |
Hb, haemoglobin; FCM, ferric carboxymaltose; ID, iron deficiency; MCV, mean corpuscular volume; TSAT, transferrin saturation.
a
Serum ferritin <300 ng/mL if transferrin saturation is <20%.