Table 2.
Clinical measures associated with disease state and extravascular lung water status
| Admission | Discharge | |
|---|---|---|
| Weight, kg | 99.5 ± 30.6 | 92.4 ± 27.1* |
| Hgb, mg dL−1 | 11.3 ± 2.3 | 12.6 ± 2.1* |
| MAP, mmHg | 95.1 ± 27.8 | 78.5 ± 11.9* |
| HR, b.p.m. | 86.3 ± 19.1 | 82.8 ± 18.5 |
| RR, b.p.m. | 17.3 ± 3.5 | 18.2 ± 3.7 |
| SpO2, % | 95.5 ± 2.8 | 96.1 ± 1.5 |
| Drugs (HFrEF, HFpEF) | ||
| ACE inhibitor | 3 (1, 2) | 4 (3, 1) |
| Angiotensin II blocker | 2 (1, 1) | 2 (1, 1) |
| Beta‐blocker | 8 (5, 3) | 12 (12, 0) |
| Digitalis | 1 (1, 0) | 3 (2, 1) |
| Diuretic | 12 (5, 7) | 15 (7, 8) |
| CT indices | ||
| Mean, HU | −813 ± 40.4 | −847 ± 50.5** |
| Skew | 2.35 ± 0.67 | 2.64 ± 0.56* |
| Kurtosis | 10.5 ± 4.40 | 12.9 ± 3.90** |
| FWHM | 125 ± 36.8 | 110 ± 28.4** |
ACE, angiotensin‐converting enzyme; CT, computed tomography; FWHM, full‐width half‐maximum; HFpEF, heart failure with preserved ejection fraction; HFrEF, heart failure with reduced ejection fraction; Hgb, haemoglobin concentration; HR, heart rate; HU, Hounsfield unit; MAP, mean arterial pressure; RR, respiratory rate; SpO2, oxygen saturation.
Patients had significant weight loss, increase in Hgb, and decrease in MAP. No change was observed between study visits in HR, RR, or SpO2. Patient drug regimens were optimized during inpatient treatment. Quantitative CT indices are representative of extravascular lung water status. Decreased mean, increased skew, increased kurtosis, and FWHM are indicative of fluid clearance. Data are mean ± standard deviation.
P < 0.01,
P < 0.05.