Table 3.
Cox regression analysis of N‐terminal pro‐B‐type natriuretic peptide corrected for ethnicity
| Adjustments | Cox HRa (95% CI) | P‐value | Total | Caucasian | Asian |
|---|---|---|---|---|---|
| P‐value interaction (ethnicity) | P‐value interaction (HF status) | P‐value interaction (HF status) | |||
| Univariable | 1.28 (1.21–1.35) | <0.001 | NA | 0.338 | 0.077 |
| Ethnicity | 1.28 (1.21–1.35) | <0.001 | 0.631 | NA | NA |
| Model 1 | 1.26 (1.19–1.33) | <0.001 | 0.520 | 0.865 | 0.092 |
| Model 2 | 1.23 (1.15–1.31) | <0.001 | 0.825 | 0.411 | 0.583 |
| Model 3 | 1.28 (1.18–1.39) | <0.001 | 0.719 | 0.558 | 0.776 |
CI, confidence interval; HF, heart failure; HR, hazard ratio.
Model 1: Ethnicity, Age; Sex.
Model 2: Model 1; body mass index; estimated glomerular filtration rate; systolic blood pressure; history of peripheral vascular disease; chronic obstructive pulmonary disease; diabetes; atrial fibrillation; myocardial infarction, and New York Heart Association class.
Model 3: Model 2; left ventricular ejection fraction; usage of aldosterone antagonists; diuretics; digoxin; beta‐blockers; angiotensin‐converting enzyme inhibitors; angiotensin‐II receptor blockers.
a
Hazard ratios are per doubling of levels of N‐terminal pro‐B‐type natriuretic peptide.