TABLE 1.
Midazolam (N=40) |
Ketamine (N=40) |
||||||
---|---|---|---|---|---|---|---|
Variableb | N | % | N | % | χ2 | df | p |
Female sex | 26 | 65 | 22 | 55 | 0.83 | 1 | 0.36 |
White race | 39 | 97.5 | 35 | 87.5 | 0.20h | ||
Hispanic ethnicity | 1 | 2.5 | 0 | 0 | 1.0h | ||
Married | 7 | 18 | 7 | 18 | 0.00 | 1 | 0.96 |
Currently employed | 15 | 37.5 | 10 | 25 | 1.46 | 1 | 0.23 |
Prior psychiatric hospitalization | 29 | 73 | 27 | 68 | 0.24 | 1 | 0.63 |
Prior suicide attemptc | 22 | 55 | 17 | 42.5 | 1.25 | 1 | 0.26 |
Personality disorderd | 13 | 36 | 16 | 41 | 0.19 | 1 | 0.66 |
Borderline personality disorderd | 3 | 8 | 11 | 28 | 4.87 | 1 | 0.03 |
Alcohol or substance use disorder history | 9 | 22.5 | 11 | 27.5 | 0.27 | 1 | 0.61 |
Mood disorder in first degree relative | 23 | 57.5 | 24 | 60.0 | 0.052 | 1 | 0.82 |
Suicide or attempt in first degree relative | 3 | 7.5 | 2 | 5.0 | 1.0h | ||
Variable | N | Mean ± SD | N | Mean ± SD | t | df | p |
Age | 40 | 40.7 ±13.1 | 40 | 38.4 ±13.2 | 0.77 | 78 | 0.44 |
Scale for Suicidal Ideatione | 40 | 15.7 ±6.9 | 40 | 14.3 ±6.3 | 0.94 | 78 | 0.35 |
Hamilton Depression Rating Scale (17 item)f | 40 | 22.6 ±3.9 | 40 | 22.2 ±4.6 | 0.41 | 78 | 0.68 |
Beck Depression Inventoryg | 38 | 33.9 ±8.1 | 36 | 31.8 ±8.1 | 1.13 | 72 | 0.26 |
Total years of education | 39 | 15.9 ±2.4 | 40 | 15.9 ±2.8 | 0.04 | 77 | 0.97 |
Variable | Median (range) | Median (range) | Ui | p | |||
Length of current episode (weeks) | 37 | 50 (2–2860) | 36 | 60 (8–572) | 652.0 | 0.88 | |
Age of onset of first major depressive episode (years) | 39 | 14 (5–45) | 37 | 16 (6–51) | 744.5 | 0.81 | |
Lifetime number of major depressive episodes including current | 35 | 3 (1-too many to count) | 36 | 4.5 (1-too many to count) | 716.5 | 0.31 | |
Body mass index | 40 | 27.8 (17.2–51.5) | 40 | 25.3 (19.9–46.7) | 708.0 | 0.38 |
Modified intention-to-treat sample.
Assessed with our research Baseline Clinical-Demographic form unless otherwise noted.
Columbia Suicide History Interview (48).
SCID for DSM-IV Axis II disorders (27).
Score ranges from 0 to 38, with higher scores indicating greater symptom severity.
Score ranges from 0 to 53, with higher scores indicating greater symptom severity.
Score ranges from 0 to 63, with higher scores indicating greater symptom severity.
Fisher’s Exact Test
Mann-Whitney U