. Author manuscript; available in PMC: 2019 Apr 1.

Published in final edited form as: Gastroenterology. 2017 Dec 8;154(5):1380–1390.e5. doi: 10.1053/j.gastro.2017.12.001

Table 6.

Odds ratio of pancreatic cancer by prediagnosis plasma salicylurate levels.

	Quintiles of Plasma Salicylurate					P_trend^✚
	1 (lowest)	2	3	4	5 (highest)	P_trend^✚
No. cases/controls	79/156	82/157	80/157	66/157	89/157
OR (95% CI)^*	1	1.04 (0.71, 1.52)	1.01 (0.69, 1.49)	0.83 (0.56, 1.23)	1.11 (0.75, 1.64)	0.56
OR (95% CI)^§	1	1.09 (0.74, 1.62)	1.04 (0.70, 1.54)	0.80 (0.53, 1.20)	1.08 (0.72, 1.61)	0.81

CI, confidence interval; OR, odds ratio

OR (95% CI) from conditional logistic regression models conditioned on matching factors (year of birth, cohort, smoking status, fasting status, and month of blood draw).

^§

OR (95% CI) from conditional logistic regression models conditioned on matching factors and adjusted for race (White, Black, other, unknown), BMI in kg/m² (<25.0, 25.0–29.9, 30.0–34.9, ≥35.0, missing), diabetes mellitus (yes/no), alcohol intake in grams/day (0, 0.1–4.9, 5.0–14.9, 15.0–29.9, ≥30.0, missing), multivitamin use (yes/no), physical activity (quintiles by sex), and regular non-aspirin NSAID use (yes/no/missing).

^✚

Tests for trend conducted using the log-transformed metabolite as a continuous variable.