Table 1.
Demographics and Ocular Characteristics of the Study Population^
| Eyes with Focal LC Defect (46 Eyes, 46 Patients) | Eyes without Focal LC Defect (54 Eyes, 54 Patients) | P Value | |
|---|---|---|---|
|
| |||
| Age (yrs) | 71.45 (67.37, 75.53) | 70.82 (67.99, 73.65) | 0.794** |
|
| |||
| Gender (male/female) | 16/30 | 33/21 | 0.009‡ |
|
| |||
| Race, n | African American 9 | African American 10 | 0.656‡ |
| Caucasian 7 | White 31 | ||
| White 24 | Other 13 | ||
| Other 13 | |||
|
| |||
| Self-reported diabetes, n (%) | 6 (13.0) | 1 (1.8) | 0.029‡ |
|
| |||
| Self-reported hypertension, n (%) | 19 (41.3) | 27 (50.0?) | 0.384‡ |
|
| |||
| Spherical Equivalent (D) | −1.13 (−1.73, −0.53) | −0.64 (−1.13, −0.15) | 0.204* |
|
| |||
| CCT (μm) | 533.28 (520.50, 546.06) | 534.04 (523.91, 544.18) | 0.923¥ |
|
| |||
| IOP (mmHg) | 14.48 (12.81, 16.16) | 14.27 (13.05, 15.51) | 0.835¥ |
|
| |||
| Axial length (mm) | 24.14 (23.64, 24.66) | 24.03 (23.68, 24.38) | 0.702¥ |
|
| |||
| SBP (mmHg) | 127.02 (122.03, 132.02) | 125.16 (121.04, 129.29) | 0.560¥ |
|
| |||
| DBP (mmHg) | 80.19 (77.04, 83.35) | 77.29 (74.62, 79.97) | 0.160¥ |
|
| |||
| MOPP (mmHg) | 54.78 (52.12, 57.46) | 52.97 (51.12, 54.82) | 0.247¥ |
|
| |||
| VF MD (dB) | −5.63 (−7.47, −3.80) | −4.64 (−6.20, −3.08) | 0.404* |
|
| |||
| VF PSD (dB) | 5.68 (4.52, 6.84) | 4.79 (3.80, 3.05) | 0.242* |
|
| |||
| Disc area (mm2) | 2.03 (1.91, 2.15) | 2.05 (1.93, 2.18) | 0.782¥ |
|
| |||
| RNFL thickness (μm) | 76.14 (72.45, 79.83) | 78.79 (74.65, 82.93) | 0.347¥ |
^
Unless otherwise indicated, continuous variables are shown as mean (95% CI)
LC: lamina cribrosa; D: diopters; CCT: central corneal thickness; IOP: intraocular pressure; SBP: systolic blood pressure; DBP: diastolic blood pressure; MOPP: mean ocular perfusion pressure; VF MD: visual field mean deviation; VF PSD: visual field pattern standard deviation; dB: decibels; RNFL: retinal nerve fiber layer.
*
Comparison was performed by using the Mann Whitney test.
‡
Comparison was performed by using the chi-square test.
¥
Comparison was performed by using independent samples t test.