Table 1.

Demographic, health, and substance use disorder characteristics and cytokine levels of patients (n=80) in 5 Norwegian alcohol & drug treatment centers

	Psychological distress case negative	Psychological distress case positive
	n=64	n=16
Characteristics	n (%)	n (%)	p-value
Demographics
Age (mean, SD)	40.7 (12.8)	47.0 (8.6)	0.069
Male	47 (73.4)	10 (62.5)	0.387
Single/never married	44 (68.8)	8 (50.0)	0.26
Full-time employment past 6 months	7 (11.1)	2 (12.5)	0.415
Health
Chronic disease present	25 (39.1)	4 (25.0)	0.295
Weekly/daily over the counter medication use	31 (48.4)	1 (6.3)	0.002
Substance use disorders
Past year AUD only	30 (37.5)	8 (26.7)	0.248
Past year DUD only	24 (30.0)	2 (12.5)	0.088
Past year comorbid AUD and DUD	14 (17.5)	3 (18.8)	0.883
Cytokines
IL-6 (mean, SD)	2.3 (0.42)	2.4 (0.12)	0.231
TNF-a (mean, SD)	3.9 (0.30)	3.9 (0.47)	0.784
INF-g (mean, SD)	4.8 (0.46)	4.9 (0.46)	0.279
IL-10 (mean, SD)	2.6 (0.50)	2.6 (0.61)	0.833

Note: AUD = Alcohol Use Disorder; DUD = Drug Use Disorder; SCL-90-R=Symptom Checklist 90-Revised; all cytokine values were log transformed.