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. Author manuscript; available in PMC: 2019 Apr 1.
Published in final edited form as: J Orthop Res. 2017 Nov 22;36(4):1153–1163. doi: 10.1002/jor.23754

Table 3.

Candidate list of proteins chosen after sorting the proteins based on ANOVA FDR q-value and the maximum fold change. The canonical pathways enriched by each protein is listed. Canonical pathway A: NF-κB Signaling; B: IL-6 Signaling; C: VEGF Signaling; D: Apoptosis Signaling; E: Wnt/β-catenin Signaling; F: TGF-β Signaling; G: FGF Signaling; H: BMP signaling pathway. Expression values are listed in Supplemental material.

# Target In Pathway # Target In Pathway
1 WIF-1 E 26 KPCT A, D
2 JNK2 B, F, H 27 IGF-I sR A
3 Caspase-10 D 28 IGF-II receptor A
4 RSK-like protein kinase G 29 SMAD3 F
5 KREM2 E 30 SMAD2 F
6 FGF7 G 31 BMP-7 F, H
7 CD40 ligand, soluble A 32 RANK A
8 FGF-6 G 33 MP2K4 B, D, F, H
9 VEGF121 B, C 34 MK12 B, F, G, H
10 TGF-b R III A, E 35 CRK G
11 FGF-16 G 36 DKK1 E
12 VEGF-C C 37 TLR4 A
13 WNT7A E 38 Dkk-4 E
14 TrkC A 39 UBE2N A
15 BAD A, B 40 RAC1 G
16 PDGF Rb A 41 SHC1 B, C
17 ZAP70 A 42 Insulin A
18 Activin AB F 43 PRKACA A, H
19 VEGF sR3 A, C 44 FGF-18 G
20 Cadherin-5 E 45 FST H
21 TBK1 A 46 GRB2 adapter protein A, B, C, F, G, H
22 Cadherin-12 E 47 PKC-B-II A, C
23 IL-1 R AcP B 48 PKC-B-II C
24 bFGF-R A, B, C, G 49 EGFRvIII A
25 IL-1Ra A, B 50 SPTA2 D