Table 1.
Participant characteristics at baseline and post-RYGB
| Non-obese control (N = 20) | Obese pre-surgery (N = 22) | Obese post-surgery (N = 22) | P value control vs. pre-surgery | P value pre- vs. post-surgery | |
|---|---|---|---|---|---|
| Age (years)* | 46.0 (2.6) | 47.0 (1.2) | – | 0.720 | – |
| Sex—N (%) female | 12 (60) | 4 (18) | – | 0.175† | – |
| Smoking—N (%) | |||||
| Daily | 5 (25) | 0 | 1 (5) | 0.002† | < 0.001‡ |
| Occasional | 1 (5) | 0 | 11 (52) | ||
| Ex-smoker | 2 (10) | 11 (50) | 9 (43) | ||
| Never smoked | 12 (60) | 10 (45) | 0 | ||
| Missing data | 0 | 1 (4) | 0 | ||
| NSAID use—N (%) | 5 (25) | 10 (45) | 1 (5) | 0.209† | 0.004§ |
| Previous cholecystectomy—N (%) | 2 (10) | 4 (18) | – | 0.665† | – |
| Weight (kg)* | 71.8 (2.8) | 114.8 (3.7) | 86.3 (3.5) | < 0.001 | < 0.001 |
| BMI (kg/m2)* | 25.4 (0.5) | 42.4 (1.4) | 31.3 (1.2) | < 0.001 | < 0.001 |
| Body fat (%)* | 30.3 (1.3) | 47.6 (1.0) | 36.1 (1.5) | < 0.001 | < 0.001 |
| Waist (cm)* | |||||
| Men | 95.9 (2.9) | 137.3 (2.0) | 112.5 (4.5) | < 0.001 | 0.007 |
| Women | 83.4 (2.2) | 117.5 (2.2) | 91.9 (3.5) | < 0.001 | < 0.001 |
| Waist to hip ratio* | |||||
| Men | 0.93 (0.01) | 1.07 (0.03) | 0.99 (0.03) | 0.001 | 0.067 |
| Women | 0.82 (0.02) | 0.89 (0.01) | 0.84 (0.02) | 0.010 | 0.007 |
Independent sample t test used to compare non-obese control and obese pre-surgery participants, unless otherwise indicated. Paired sample t test used to compare participants pre- and post-surgery, unless otherwise indicated
NSAID non-steroidal anti-inflammatory agent
*Values indicate mean (SEM)
†Fisher’s exact test
‡Wilcoxon sign test
§Related sample McNemar test