Table 4.

Rectal mucosal crypt cell proliferation state and crypt dimensions

	Non-obese control (N = 20)	Obese pre-surgery (N = 22)	Obese post-surgery (N = 22)	P value control vs. pre-surgery	P value pre- vs. post-surgery
Total mitoses per crypt	5.9 (1.0)	6.5 (0.9)	4.3 (0.5)	0.640	0.028
Mitoses in top half of the crypt (%)	6.7 (1.5)	9.1 (1.7)	5.9 (1.2)	0.199	0.047
Crypt length (mm)	0.53 (0.01)	0.53 (0.02)	0.55 (0.01)	0.591	0.448
Crypt width (mm)	0.12 (0.003)	0.11 (0.004)	0.12 (0.002)	0.360	0.212
Crypt area (mm2)	0.21 (0.01)	0.20 (0.01)	0.21 (0.01)	0.786	0.282

Data are presented as mean (SEM). Independent sample t test used to compare non-obese control and obese pre-surgery participants. Paired sample t test used to compare participants pre- and post-surgery