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. 2018 Mar 29;33(2):178–203. doi: 10.1007/s12928-018-0516-y

Table 1.

Major differences in available medication and mechanical devices

Europe Japan
Glycoprotein IIb/IIIa inhibitors Tirofiban, eptifibatide, and abciximab are available GP IIb/IIIa inhibitors are not available
P2Y12 inhibitors The preferred P2Y12 inhibitors are prasugrel [60 mg loading dose and 10 mg maintenance dose once daily per os (p.o.)] or ticagrelor (180 mg p.o. loading dose and 90 mg maintenance dose twice daily) Both prasugrel and ticagrelor are available, but the dose in prasugrel is different. [20 mg loading dose and 3.75 mg maintenance dose once daily per os]
Mechanical LV assist devices Intra-cardiac axial flow pump (i.e. Impella) and intra-aortic balloon pump are available Intra-aortic balloon pump is used. Intra-cardiac axial flow pump (i.e. Impella) is not widely available but used in limited institutions