Table 2.
Major CE approved DES and their availability in Japan
| DES | Stent platform | Polymer coating | Drug | Availability in Japan |
|---|---|---|---|---|
| Based on durable polymer coatings | ||||
| DESyne Nx | Cobalt-chrome | PBMA | Novolimus | No |
| Promus element | Platinum-chrome | PBMA and PVDF-HFP | Everolimus | Yes |
| Resolute | Cobalt-chrome | PBMA, PHMA, PVP, and PVA | Zotarolimus | Yes |
| STENTYS | Nitinol | PSU and PVP | Paclitaxel | No |
| Xience | Cobalt-chrome | PBMA and PVDF-HFP | Everolimus | Yes |
| Based on biodegradable polymer coatings | ||||
| Axxess | Nitinol | PDLLA | Biolimus A9 | No |
| Biomatrix | Stainless steel | PDLLA | Biolimus A9 | No |
| BioMime | Cobalt-chrome | PLLA and PLGA | Sirolimus | No |
| Combo | Stainless steel | PDLLA and PLGA + additional coating with anti-CD34 | Sirolimus | No |
| DESyne BD | Cobalt-chrome | PLLA | Novolimus | No |
| Infinnium | Stainless steel | PLLA, PLGA, PCL, and PVP | Paclitaxel | No |
| MiStent | Cobalt-chrome | PLGA | Crystalline sirolimus | No |
| Nobori | Stainless steel | PDLLA | Biolimus A9 | Yes |
| Orsiro | Cobalt-chrome | PLLA | Sirolimus | Yes |
| Supralimus Core | Cobalt-chrome | PLLA, PLGA, PCL, and PVP | Sirolimus | No |
| Synergy | Platinum-chrome | PLGA | Everolimus | Yes |
| Ultimaster | Cobalt-chrome | PDLLA and PCL | Sirolimus | Yes |
| Yukon Choice PC | Stainless steel | PDLLA | Sirolimus | No |
| Polymer-free | ||||
| Amazonia Pax | Cobalt-chrome | – | Paclitaxel | No |
| BioFreedom | Stainless steel | – | Biolimus A9 | Yes |
| Cre8 | Cobalt-chrome | – | Sirolimus | No |
| Yukon Choice PF | Stainless steel | – | Sirolimus | No |
| Coroflex ISAR | Cobalt-chrome | – | Sirolimus | No |