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Minimum inhibitory concentration (MIC) and cyp51A sequencing of azole-resistant isolates.
| Patient n° |
cyp51a mutation (typing) |
MIC Etest® (mg/L) |
|||
|---|---|---|---|---|---|
| Nucleotide sequence | Amino acid sequence | VRC | ITC | POS | |
| 1 | None | None | 16 | 32 | 0.094 |
| 2 | t293a | TR34/L98H | >32 | >32 | >32 |
| 3 | t659a | M220K | 1.5 | >32 | >32 |
| 4 | g160a | G54R | 0.25 | >32 | >32 |
| 5 | None | None | 8 | 32 | 4 |
MIC, minimum inhibitory concentration; VRC, voriconazole; ITC, itraconazole; POS, posaconazole.
