Table 4.
Neuropsychological exam findings in adults with West Nile virus infection by acute clinical presentation.
| Domain | Non-neuro n = 76 (%) | Neuroinvasive n = 35 (%) | Univariate p-value | Multivariatea p-values | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Neurological Screening | ||||||||||||||
| Glasgow Coma Scale | 15.0 (0.0) | 15.0 (0.0) | NS | – | ||||||||||
| Glasgow Outcome Scale | 5.0 (0.0) | 4.9 (0.0) | NS | – | ||||||||||
| GOAT | 96.9 (0.4) | 94.8 (0.6) | 0.004 | 0.030 | ||||||||||
| Neurocognitive | ||||||||||||||
| WASI matrix reasoning | 52.5 (1.2) | 50.7 (1.8) | NS | – | ||||||||||
| RBANS total | 100.2 (2.0) | 91.0 (3.1) | 0.013 | 0.060 | ||||||||||
| Immediate memory | 94.3 (2.0) | 86.8 (3.2) | 0.050 | NS | ||||||||||
| Delayed memory | 97.6 (2.0) | 91.1 (3.1) | NS | – | ||||||||||
| Visuospatial | 108.0 (1.8) | 98.2 (2.8) | 0.004 | 0.011 | ||||||||||
| Language | 96.9 (1.2) | 93.5 (1.9) | NS | – | ||||||||||
| Attention | 104.1 (2.3) | 99.9 (3.5) | NS | – | ||||||||||
| Token test | 33.9 (0.4) | 33.6 (0.6) | NS | – | ||||||||||
| Mood | ||||||||||||||
| Beck depression inventory | 8.9 (1.2) | 10.0 (1.8) | NS | – | ||||||||||
| Functioning | ||||||||||||||
| Barthel ADL Index | 100.0 (0.6) | 95.9 (0.9) | <0.001 | 0.004 | ||||||||||
| Short Form-36 | 99.4 (1.2) | 96.3 (1.8) | NS | – | ||||||||||
GOAT, Galveston Orientation and Amnesia Test; RBANS, Repeatable Battery for the Assessment of Neuropsychological Status; WASI, Wechsler Abbreviated Scale of Intelligence.
aAnalyses controlled for age and education.