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. 2018 Mar 23;21(1):1–10. doi: 10.4048/jbc.2018.21.1.1

Table 4. Trends in age-standardized incidence rates for breast cancer according to joinpoint analysis (1999–2015).

	AAPC 1999–2015	Trend 1				Trend 2
		Period	APC	95% CI		Period	APC	95% CI
		Period	APC	Lower	Higher	Period	APC	Lower	Higher
All breast cancer	+6.2^*	1999–2007	+7.9^*	6.9	8.9	2007–2015	+4.5^*	3.5	5.5
Invasive breast cancer	+5.6^*	1999–2005	+7.7^*	6.0	9.4	2005–2015	+4.4^*	3.6	5.1
Carcinoma in situ	+13.3^*	1999–2008	+18.6^*	17.0	20.2	2008–2015	+6.9^*	4.8	9.0

9.0AAPC=average annual percentage change (%); APC=annual percent change (%); CI=confidence interval.

^*The APC or AAPC is a significantly different from zero (p<0.05).