Figure 5. Exfoliative cytology of the left nipple. The anaplastic cells with intranuclear cytoplasmic invaginations, and the prominent nucleoli can be seen using (A) Papanicolaou stain (×400; inset, ×1,000) and (B) Giemsa stain (×1,000). These melanocytes also revealed strong immunohistochemical reactions for (C) Melan-A (×1,000) and (D) HMB45 (×1,000).