Table 2.
Variable | Pre-intervention | Post-intervention |
---|---|---|
| ||
HDL mediated cholesterol efflux, % | 3.93 ± 1.16 | 4.13 ± 1.40* |
Fluidity of the HDL monolayer, 1/AU | 4.96 ± 0.48 | 5.00 ± 0.34 |
HDL composition | ||
Fatty acids in HDL, % | ||
Arachidonic | 10.32 ± 5.13 | 10.61 ± 7.06 |
Eicosatreanoic | 0.77 ± 1.56 | 0.61 ± 1.15 |
Linoleic | 29.40 ± 9.55 | 27.78 ± 15.36 |
Oleic | 19.61±7.26 | 20.78 ± 7.15† |
Palmitic | 22.33 ±14.13 | 23.61 ± 7.27 |
Stearic | 10.93 ±10.04 | 11.55 ± 6.85 |
Proteins in HDL, g/L | ||
Apolipoprotein A-I | 0.63 ± 0.16 | 0.66 ± 0.17† |
Apolipoprotein A-II | 0.17 ± 0.05 | 0.17 ± 0.04 |
Lipids in HDL, mg/dL | ||
Total Cholesterol | 31.84 ± 11.60 | 31.82 ± 12.05 |
Free Cholesterol | 13.42 ± 6.25 | 12.73 ± 5.86 |
Esterified cholesterol | 18.41 ± 8.05 | 18.45 ± 8.07 |
Triglycerides | 7.22 ± 2.09 | 7.28 ± 2.24 |
Phospholipids | 61.13 ± 18.44 | 60.66 ± 17.71 |
Oxidative status of HDLa | ||
Lag time, minb | 34.09 (26.60–52.78) | 35.38 (26.94–46.07) |
Maximum absorbance, Abs | 0.48 ± 0.10 | 0.47 ± 0.14 |
Oxidation rate, Abs/s | 7.96 ± 2.52 | 8.14 ± 2.52 |
Antioxidative status of HDL, µmols/L | ||
Total phenolic contentb c | 14.41 (0–144.5) | 63.78 (0–585.3)‡ |
α-tocopherol | 12.64 ± 0.70 | 12.77 ± 0.79* |
γ-tocopherol | 0.13 ± 0.35 | 0.15 ± 0.44 |
β-caroteneb | 1.27 (0–3.18) | 1.79 (0–3.45) |
β -cryptoxanthin | 7.95 ± 2.96 | 8.73 ± 3.44‡ |
Coenzime-Q | 299.2 ± 192.2 | 324.2 ± 191.1† |
Luteine | 2.26 ± 1.93 | 2.58 ± 2.02 |
Retinol | 3.39 ± 1.67 | 3.71 ± 2.01 |
PON1 activity, U/Ld | 5.18 ± 1.58 | 5.31± 1.74 |
HDL particle size, µmol/L | ||
HDL mean size (total)e | 9.24 ± 0.46 | 9.27 ± 0.45 |
Small HDL particles | 17.71 ± 6.03 | 16.93 ± 5.32 |
Medium HDL particles | 10.80 ± 6.09 | 9.35 ± 4.96 |
Large HDL particles | 7.07 ± 3.68 | 7.09 ± 3.53 |
Values expressed as mean and standard deviation. AU, arbitrary units
Conjugated dienes formation curve.
Values expressed as median (25th-75th percentile)
Expressed in nmol/L.
PON1, Paraoxonase-1.
Expressed in nanometers.
P<0.05;
P<0.01;
P<0.001