Table 1. Clinicopathologic characteristic of all matched patients.
Variables | LNN group (n=36) | LNP group (n=36) | P-value | |
---|---|---|---|---|
Sex | Male | 20 (55.6) | 20 (55.6) | 1.000 |
Female | 16 (44.4) | 16 (44.4) | ||
Age (yr) | 61.6±11.1 | 64.0±11.2 | 0.366 | |
BMI (kg/m2) | 23.0±3.0 | 24.9±3.8 | 0.020 | |
Previous ESD | 1 (2.8) | 3 (8.3) | 0.615 | |
cT-stage | cT1 | 23 (63.9) | 18 (50.0) | 0.491 |
cT2 | 8 (22.2) | 11 (30.6) | ||
cT3 | 3 (8.3) | 6 (16.7) | ||
cT4 | 2 (5.6) | 1 (2.8) | ||
cN-stage | N0 | 27 (75.0) | 21 (58.3) | 0.417 |
N1 | 7 (19.4) | 11 (30.6) | ||
N2 | 2 (5.6) | 3 (8.3) | ||
N3 | 0 (0) | 1 (2.8) | ||
Resection | Total gastrectomy | 2 (5.6) | 2 (5.6) | 0.767 |
Completion total gastrectomy | 0 (0) | 1 (2.8) | ||
Distal gastrectomy | 30 (83.3) | 30 (83.3) | ||
Proximal gastrectomy | 4 (11.1) | 3 (8.3) | ||
Extent of LND | D1 | 0 (0) | 1 (2.8) | 0.599 |
D1+ | 21 (58.3) | 20 (55.6) | ||
D2 | 15 (41.7) | 15 (41.7) | ||
Tumor depth | M | 5 (13.9) | 4 (11.1) | 0.242 |
Sm | 1 (2.8) | 0 (0) | ||
Sm1 | 5 (13.9) | 8 (22.2) | ||
Sm2 | 9 (25.0) | 3 (8.3) | ||
Sm3 | 16 (44.4) | 21 (58.3) | ||
pTstage | pT1a | 5 (13.9) | 4 (11.1) | 0.722 |
pT1b | 31 (86.1) | 32 (88.9) | ||
pNstage/pStage | N0/stage Ia | 36 (100.0) | 0 (0) | <0.001 |
N1/stage Ib | 0 (0) | 22 (61.1) | ||
N2/stage IIa | 0 (0) | 8 (22.2) | ||
N3/stage IIb | 0 (0) | 6 (16.7) | ||
Differentiation | Differentiated | 12 (33.3) | 12 (33.3) | 1.000 |
Undifferentiated | 24 (66.7) | 24 (66.7) | ||
Lauren | Intestinal | 10 (27.8) | 13 (36.1) | 0.592 |
Mixed | 11 (30.6) | 12 (33.3) | ||
Diffuse | 15 (41.7) | 11 (30.6) | ||
Lymphatic invasion | Present | 6 (16.7) | 33 (91.7) | <0.001 |
Absent | 30 (83.3) | 3 (8.3) | ||
Vascular invasion | Present | 0 (0) | 2 (5.6) | 0.151 |
Absent | 36 (100.0) | 34 (94.5) | ||
Perineural invasion | Present | 2 (5.6) | 4 (11.1) | 0.394 |
Absent | 34 (94.4) | 32 (88.9) | ||
Growth pattern | Expansile | 4 (11.1) | 2 (5.6) | 0.526 |
Intermediate | 14 (38.9) | 18 (50.0) | ||
Infiltrative | 18 (50.0) | 16 (44.4) | ||
Tumor size (cm) | 3.6±2.2 | 3.8±1.8 | 0.646 | |
No. of retrieved LN | 37.3±19.8 | 40.5±11.6 | 0.408 |
Continuous variables were described as mean±standard deviation and nominal variables were described as numbers (%).
LNN = lymph node-negative; LNP = lymph node-positive; BMI = body mass index; ESD = endoscopic submucosal dissection; LND = lymph node dissection; M = mucosa; Sm = submucosa; LN = lymph node.