Table 3. Univariable and multivariable analysis of prognostic factors for RFS after propensity score matching.
Variable | No. of patients | Univariable | Multivariable | |||
---|---|---|---|---|---|---|
HR (95% CI) | P-value | HR (95% CI) | P-value | |||
Age (yr) | ||||||
<70 | 313 | 1 | - | |||
≥70 | 35 | 1.12 (0.48–2.61) | 0.793 | |||
Sex | ||||||
Female | 111 | 1 | - | |||
Male | 237 | 1.28 (0.72–2.28) | 0.395 | |||
Surgical approach | ||||||
Laparoscopy | 246 | 1 | - | 1 | - | |
Open | 102 | 1.82 (1.08–3.07) | 0.024 | 1.62 (0.95–2.74) | 0.075 | |
Body mass index (kg/m2) | 1.05 (0.96–1.15) | 0.279 | - | - | ||
Type of operation | ||||||
Distal gastrectomy | 245 | 1 | - | |||
Total gastrectomy | 103 | 1.34 (0.78–2.30) | 0.296 | |||
Complications within 30 days (grade II or more) | ||||||
No | 337 | 1 | - | |||
Yes | 11 | 1.14 (0.28–4.69) | 0.852 | |||
Histological type | ||||||
Differentiated | 105 | 1 | - | 1 | - | |
Undifferentiated | 243 | 2.03 (1.05–3.92) | 0.035 | 2.05 (1.06–3.96) | 0.033 | |
Stage | ||||||
II | 155 | 1 | - | 1 | - | |
III | 193 | 2.83 (1.55–5.17) | 0.001 | 2.61 (1.42–4.80) | 0.002 | |
Time to CTx (wk) | ||||||
≤4 | 174 | 1 | - | 1 | - | |
>4 | 174 | 1.04 (0.62–1.74) | 0.889 | 1.05 (0.62–1.75) | 0.866 |
RFS = relapse-free survival; HR = hazard ratio; CI = confidence interval; CTx = chemotherapy.