Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Engineering of industrial high-yielding S. erythraea strain E3 for increased erythromycin production. Supernatants (cultivated in industrial fermentation medium or industrial fermentation medium plus 30 mM valine) were collected after being cultivated for about 7 days. Erythromycin was measured by HPLC as described in Materials and Methods. Three independent replicates were used to calculate the standard deviations. **, P < 0.01; ****, P < 0.0001.
