Table 3.
Cortical thickness information from the analysis between HCs and PD patients.
| Cortical area | Cluster size (mm2) | Stats | P-value | MNI coordinates (x y z)1 |
|---|---|---|---|---|
| PD patients < healthy controls at p < 0.05 | ||||
| Left superior parietal | 20,272.3 | 3.826 | 0.0002 | −24 −82 23 |
| Right lingual | 25,478.3 | 4.274 | 0.0002 | 10 −59 −0 |
| PD patients < healthy controls at p < 0.01 | ||||
| Left superior parietal | 11,282.9 | 3.826 | 0.0002 | −24 −82 23 |
| Right lingual | 4059.7 | 4.274 | 0.0002 | 10 −59 −0 |
| Right superior parietal | 9925.9 | 4.256 | 0.0002 | 27 −59 47 |
| PD patients < healthy controls with GWC as per-vertex regressor at p < 0.05 | ||||
| Left superior parietal | 20,330.9 | 3.719 | 0.0002 | −22 −84 21 |
| Right lingual | 22,992.3 | 4.531 | 0.0002 | 11 −57 −0 |
| PD patients < healthy controls with GWC as per-vertex regressor at p < 0.01 | ||||
| Left superior parietal | 8371.8 | 3.719 | 0.0002 | −22 −84 21 |
| Left supramarginal | 1794.7 | 3.213 | 0.0272 | −50 −52 39 |
| Right lingual | 3349.2 | 4.531 | 0.0004 | 11 −57 −0 |
| Right superior parietal | 101,165 | 4.067 | 0.0002 | 27 −60 47 |
| PD patients < healthy controls with GWC as per-vertex regressor at p < 0.0001 | ||||
| Right lingual | 208.3 | 4.531 | 0.0286 | 11 −57 −0 |
1MNI305 space. Abbreviations: GWC, gray to white matter contrast; PD, Parkinson’s disease; MNI, Montreal Neurological Institute. Results were obtained using Monte Carlo simulation with 10.000 iterations applied to cortical thickness maps to provide cluster-wise correction for multiple comparisons (1.3, 2.0 and 4.0). Significant clusters were reported at p < 0.05.