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. 2018 Mar 29;12:657–671. doi: 10.2147/DDDT.S155115

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© 2018 Bagheri et al. This work is published and licensed by Dove Medical Press Limited

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Gene expression analysis using RT-PCR in HT29 cells after 24 h of treatment with BJEE.

Notes: Quantitative analysis of gene expression results illustrated significant elevation in the expression of Bcl-2, Bax, p53, Cas-3, -8, and -9 genes, compared to the untreated control group. Meanwhile, gene expression of NF-κB was slightly inhibited but it has not revealed statistical significant changes. The gene expressions were shown in 2 log fold changes of mean ± SD. *p<0.05 versus control group.

Abbreviations: BJEE, Brucea javanica ethanolic extract; RT-PCR, real-time quantitative polymerase chain reaction.