Table 1.
Comparison of the indications for hepatic resection
| Region/ Year | Guidelines | Liver function factor | Tumor factor | Comment | ||||
|---|---|---|---|---|---|---|---|---|
| Child‐Pugh | Portal hypertension | ICG test | Size and number | Vascular invasion | ||||
| Europe | ||||||||
| 2012 | EASL‐EORTC | European Association for Study of Liver, European Organization for Research and Treatment of Cancer | A | No PH | (+) | Single | No VI | Based on BCLC |
| 2012 | ESMO‐ESDO | European Society for Medical Oncology | A | No PH | (−) |
Single, size ≤5 cm or ≤3 nodules, size ≤3 cm |
No VI | Based on BCLC |
| USA | ||||||||
| 2017 | AASLD | American Association for the Study of Liver Disease | A | Minimal/no PH | (−) |
Single, size ≤5 cm or ≤3 nodules, size ≤3 cm |
No VI | |
| 2017 | NCCN | National Comprehensive Cancer Network | A, B | Mild/no PH | (−) | UNOS criteria | No major VI | Based on resectability |
| Asia | ||||||||
| 2012 | Chinese | Primary Liver Cancer Diagnosis and Treatment Expert Panel of the Chinese Ministry of Health | A | (−) | (+) | ≤3 nodules | Limited intrahepatic | Choice of palliative hepatectomy |
| 2012 | Saudi | Saudi Association for the Study of Liver Disease and Transplantation; Saudi Oncology Society | A, early B | No PH | (−) |
Multinodular (resectable) |
No VI | Based on BCLC |
| 2014 | INASL | The Indian National Association for Study of the Liver | A, B | Mild/no PH | (+) |
Single or ≤3 nodules, size ≤3 cm |
No VI | Based on BCLC |
| 2015 | JSH | Japan Society of Hepatology | A, B | (−) | (+) | ≤3 nodules | If resectable | Vascular invasion is not excluded |
| 2015 | KLCSG | Korean Liver Cancer Study Group and National Cancer Center | A, superb B | Mild/no PH | (+) | ≤3 nodules | No VI | mUICC staging system |
| 2017 | APASL | Asian Pacific Association for the Study of the Liver | A, B | (−) | (+) | Resectable | No VI | Resectability should be judged by a multidisciplinary team |
United Network for Organ Sharing (UNOS) criteria, single lesion ≤5 cm, or 2 or 3 nodules ≤3 cm; BCLC, Barcelona Clinic Liver Cancer; ESDO, European Society of Digestive Oncology; ICG, indocyanine green retention test; mUICC, modified UICC; PH, portal hypertension; VI, vascular invasion; (−), excluded as a factor; (+), included as a factor.