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. 2018 Mar 7;7(4):511–522. doi: 10.1530/EC-18-0023

Table 3.

Baseline characteristics of subjects when population-based TSH reference range (0.62–6.68 µIU/mL) is used.

Total subjects (n = 4801) Subclinical hypothyroidism P value
No (n = 4644) Yes (n = 157)
Age (years) 0.011
 19–29 984 (20.4%) 957 (20.6%) 27 (17.2%)
 30–39 882 (18.4%) 863 (18.5%) 19 (12.2%)
 40–49 939 (19.6%) 904 (19.5%) 35 (22.3%)
 50–59 997 (20.8%) 950 (20.5%) 47 (29.9%)
 60–69 908 (18.9%) 883 (19.0%) 25 (15.9%)
 70 and above 91 (1.9%) 87 (1.9%) 4 (2.5%)
Sex <0.001
 Male 2498 (53.9%) 2440 (54.5%) 58 (36.4%)
 Female 2303 (46.1%) 2204 (45.5%) 99 (63.6%)
BMI (kg/m2) 0.944
 <18.5 207 (4.0%) 199 (4.0%) 8 (4.2%)
 ≥18.5, <23 1859 (38.3%) 1795 (38.2%) 64 (38.9%)
 ≥23, <25 1141 (24.2%) 1103 (24.2%) 38 (25.7%)
 ≥25 1594 (33.5%) 1547 (33.6%) 47 (31.2%)
Region of residencea 0.076
 Rural 1293 (25.7%) 1258 (25.9%) 35 (19.1%)
 Urban 3508 (74.3%) 3386 (74.1%) 122 (80.9%)
Family history of thyroid disease 0.119
 No 4565 (95.1%) 4411 (95.0%) 154 (98.0%)
 Yes 236 (4.9%) 233 (5.0%) 3 (2.0%)
Smoking <0.001
 No 2641 (54.5%) 2534 (54.0%) 107 (70.8%)
 Yes 2160 (45.5%) 2110 (46.0%) 50 (29.2%)
UICRb <0.001
 Quartile 1 1226 (25.1%) 1204 (25.5%) 22 (11.8%)
 Quartile 2 1196 (25.0%) 1167 (25.2%) 29 (21.9%)
 Quartile 3 1179 (24.9%) 1140 (25.0%) 39 (24.0%)
 Quartile 4 1200 (25.0%) 1133 (24.3%) 67 (42.3%)
Anti-TPO Ab <0.001
 Absence 4472 (93.4%) 4357 (94.1%) 115 (72.2%)
 Presence 329 (6.6%) 287 (5.9%) 42 (27.8%)
CKD stage 0.099
 Stage 1, 2 4627 (96.0%) 4474 (96.1%) 153 (98.3%)
 Stage 3, 4, 5 174 (4.0%) 170 (3.9%) 4 (1.7%)

*Data are presented as mean ± s.d., n (weighted %), statistics were carried out using Rao-Scott Chi-square test; aclassification of the area of residence is classified according to the administrative division of Korea; biodine intake status was evaluated by urine iodine creatinine ratio, quartile 1: <Q1 (141.53203438), quartile 2: ≥Q1 and <Q2 (281.81447737), quartile 3: ≥Q2 and <Q3 (664.64655625), quartile 4: ≥Q3.