Table 3.
Baseline characteristics of subjects when population-based TSH reference range (0.62–6.68 µIU/mL) is used.
| Total subjects (n = 4801) | Subclinical hypothyroidism | P value | ||
|---|---|---|---|---|
| No (n = 4644) | Yes (n = 157) | |||
| Age (years) | 0.011 | |||
| 19–29 | 984 (20.4%) | 957 (20.6%) | 27 (17.2%) | |
| 30–39 | 882 (18.4%) | 863 (18.5%) | 19 (12.2%) | |
| 40–49 | 939 (19.6%) | 904 (19.5%) | 35 (22.3%) | |
| 50–59 | 997 (20.8%) | 950 (20.5%) | 47 (29.9%) | |
| 60–69 | 908 (18.9%) | 883 (19.0%) | 25 (15.9%) | |
| 70 and above | 91 (1.9%) | 87 (1.9%) | 4 (2.5%) | |
| Sex | <0.001 | |||
| Male | 2498 (53.9%) | 2440 (54.5%) | 58 (36.4%) | |
| Female | 2303 (46.1%) | 2204 (45.5%) | 99 (63.6%) | |
| BMI (kg/m2) | 0.944 | |||
| <18.5 | 207 (4.0%) | 199 (4.0%) | 8 (4.2%) | |
| ≥18.5, <23 | 1859 (38.3%) | 1795 (38.2%) | 64 (38.9%) | |
| ≥23, <25 | 1141 (24.2%) | 1103 (24.2%) | 38 (25.7%) | |
| ≥25 | 1594 (33.5%) | 1547 (33.6%) | 47 (31.2%) | |
| Region of residencea | 0.076 | |||
| Rural | 1293 (25.7%) | 1258 (25.9%) | 35 (19.1%) | |
| Urban | 3508 (74.3%) | 3386 (74.1%) | 122 (80.9%) | |
| Family history of thyroid disease | 0.119 | |||
| No | 4565 (95.1%) | 4411 (95.0%) | 154 (98.0%) | |
| Yes | 236 (4.9%) | 233 (5.0%) | 3 (2.0%) | |
| Smoking | <0.001 | |||
| No | 2641 (54.5%) | 2534 (54.0%) | 107 (70.8%) | |
| Yes | 2160 (45.5%) | 2110 (46.0%) | 50 (29.2%) | |
| UICRb | <0.001 | |||
| Quartile 1 | 1226 (25.1%) | 1204 (25.5%) | 22 (11.8%) | |
| Quartile 2 | 1196 (25.0%) | 1167 (25.2%) | 29 (21.9%) | |
| Quartile 3 | 1179 (24.9%) | 1140 (25.0%) | 39 (24.0%) | |
| Quartile 4 | 1200 (25.0%) | 1133 (24.3%) | 67 (42.3%) | |
| Anti-TPO Ab | <0.001 | |||
| Absence | 4472 (93.4%) | 4357 (94.1%) | 115 (72.2%) | |
| Presence | 329 (6.6%) | 287 (5.9%) | 42 (27.8%) | |
| CKD stage | 0.099 | |||
| Stage 1, 2 | 4627 (96.0%) | 4474 (96.1%) | 153 (98.3%) | |
| Stage 3, 4, 5 | 174 (4.0%) | 170 (3.9%) | 4 (1.7%) | |
*Data are presented as mean ± s.d., n (weighted %), statistics were carried out using Rao-Scott Chi-square test; aclassification of the area of residence is classified according to the administrative division of Korea; biodine intake status was evaluated by urine iodine creatinine ratio, quartile 1: <Q1 (141.53203438), quartile 2: ≥Q1 and <Q2 (281.81447737), quartile 3: ≥Q2 and <Q3 (664.64655625), quartile 4: ≥Q3.
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