Table 3.
Demographic and laboratory data of patients with mild and severe AP
| Mild AP (n=23) | Severe AP (n=19) | p-value | |
|---|---|---|---|
| Age | 45 (33–67) | 69 (62–79) | <0.01 |
| Sex, female/male | 14/9 | 13/6 | 0.75 |
| BMI | 28.0±4.4 | 29.9±7.2 | 0.98 |
| Hospital stay, day median (minimum–maximum) | 6 (4–15) | 7 (4–32) | 0.15 |
| Nil per os, day median (minimum–maximum) | 3 (2–5) | 4 (2–12) | 0.01 |
| Death, n (%) | 0 (0) | 1 (5.2) | 0.45 |
| First measurements | |||
| WBC | 10,995 (8,370–14,980) | 10,600 (8,165–16,980) | 0.62 |
| PMNL | 931 (7,310–11,340) | 9,100 (6,120–14,935) | 0.68 |
| Lymphocyte | 1,055 (830–1,450) | 940 (560–1,535) | 0.69 |
| Hemoglobin | 12.8±2.9 | 13.7±2.8 | 0.32 |
| Hematocrit | 40.3±4.4 | 40.4±5.0 | 0.88 |
| Platelet | 289 (236–346) | 272 (217–318) | 0.57 |
| CRP | 1.7 (0.6–3.6) | 2.4 (1.2–5.5) | 0.33 |
| Glucose | 110±6 | 147±19 | 0.09 |
| ALT | 177±35 | 150±65 | 0.98 |
| AST | 198±34 | 286±96 | 0.81 |
| Albumin | 4.19±0.26 | 3.81±0.49 | <0.01 |
| BUN | 22±2 | 37±5 | <0.01 |
| Creatinine | 0.80±0.05 | 0.80±0.08 | 0.49 |
| Calcium | 9.11±0.48 | 8.62±0.76 | 0.03 |
| Amylase | 1,795±216 | 1,357±267 | 0.69 |
| IMA | 0.173 (0.146–0.195) | 0.135 (0.095–0.158) | 0.06 |
| Adjusted IMA | 0.174 (0.148–0.209) | 0.120 (0.090–0.158) | <0.01 |
| Second measurements | |||
| WBC | 8,295 (6,080–9,330) | 7,320 (5,955–11,120) | 0.69 |
| PMNL | 5,130 (4,330–7,910) | 5,560 (3,690–8,250) | 0.95 |
| Lymphocyte | 1,495 (1,300–1,920) | 1,120 (825–1,810) | 0.08 |
| Hemoglobin | 12.1±1.5 | 11.6±1.4 | 0.18 |
| Hematocrit | 34.6±7.4 | 35.0±4.3 | 0.47 |
| Platelet | 249 (203–319) | 211 (174–284) | 0.25 |
| CRP | 5.3 (1.0–8.5) | 7.6 (2.4–16.7) | 0.26 |
| Glucose | 75±3 | 79±13 | 0.10 |
| ALT | 119±19 | 123±31 | 0.76 |
| AST | 41±9 | 54±14 | 0.26 |
| Albumin | 3.77±0.39 | 3.37±0.14 | <0.01 |
| BUN | 18±2 | 33±8 | <0.01 |
| Creatinine | 0.66±0.05 | 0.74±0.10 | 0.07 |
| Calcium | 8.38±0.70 | 7.92±0.79 | 0.04 |
| IMA | 0.220 (0.167–0.334) | 0.188 (0.158–0.220) | 0.20 |
| Adjusted IMA | 0.229 (0.146–0.357) | 0.170 (0.143–0.199) | 0.06 |
Notes: Values in parenthesis demonstrate age by median (IQR) values. Data are also presented as mean ± standard deviation. Bold font indicate statistical significant p-values.
Abbreviations: ALT, alanine aminotransferase; AP, acute pancreatitis; AST, aspartate aminotransferase; BMI, body mass index; BUN, blood urea nitrogen; CRP, C-reactive protein; IMA, ischemia-modified albumin; PMNL, polymorphonuclear leucocyte; WBC, white blood cell.