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. 2018 Feb 16;8(4):523–532. doi: 10.1002/2211-5463.12390

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© 2018 The Authors. Published by FEBS Press and John Wiley & Sons Ltd.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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iPAI‐1 administration stimulates new bone formation in vivo during the repair of bone injury. (A) Micro‐CT analyses of the distal metaphyses of the femur of vehicle‐treated and iPAI‐1‐treated mice 12 days after bone marrow ablation. (B) Quantification of the newly formed bone within the ablated region of vehicle‐treated mice or iPAI‐1‐treated mice. Data represent mean ± SD for seven or eight mice/group. *P < 0.05. Sham + v: sham operation + vehicle; Sham + i: sham operation + iPAI‐1; OVX + v: OVX + vehicle; OVX + i: OVX + iPAI‐1.