Table 2.
Birth cohort | Non-Veterans a | Veterans a | Model 1 b | Model 2 c | ||||
---|---|---|---|---|---|---|---|---|
N | % | N | % | OR (95% CI) | p value | OR (95% CI) | p value | |
<65 at enrollment | ||||||||
None d | 46,867 | 60.4 | 737 | 56.3 | 1.00 | — | 1.00 | — |
Hysterectomy without BSO | 16,221 | 20.9 | 281 | 21.5 | 1.18 (1.03, 1.36) | .02 | 1.18 (1.02, 1.37) | .03 |
Hysterectomy with BSO | 14,544 | 18.7 | 292 | 22.3 | 1.26 (1.10, 1.45) | <.001 | 1.28 (1.10, 1.48) | .001 |
≥65 at enrollment | ||||||||
None d | 34,607 | 57.9 | 1,320 | 57.7 | 1.00 | — | 1.00 | — |
Hysterectomy without BSO | 12,558 | 21.0 | 496 | 21.7 | 1.07 (0.97, 1.20) | .19 | 1.09 (0.97, 1.22) | .15 |
Hysterectomy with BSO | 12,582 | 21.1 | 470 | 20.6 | 0.98 (0.88, 1.10) | .76 | 0.97 (0.87, 1.10) | .67 |
Notes: BMI = body mass index; BSO = bilateral salpingo-oophorectomy; CI = confidence interval; OR = odds ratio.
a Numbers and percents reflect those from Model 1.
b Adjusted for age (continuous), race (white, non-white), and parity (nominal).
c Adjusted for age (continuous), race (white, non-white), parity (nominal), education (ordinal), and age at menarche (nominal), BMI (continuous), pack-years of smoking (continuous), hormone therapy use (nominal); due to additional adjustments, sample sizes are smaller than in Adjustment 1 models due to missing information.
d Including women without hysterectomy but with partial, unilateral, or bilateral oophorectomy or unknown number of ovaries removed.