Table 2.
Comparison of IC50 values determined in different experimental conditions
| ID | IC50 of 49c against | IC50 of 49f against | IC50 of 49b against | IC50 of pyrimethamine against |
|---|---|---|---|---|
| P. falciparum parasite | ~0.6 nM (Ciana et al, 2013) | ~0.9 nM (Ciana et al, 2013) | > 500 nM (Ciana et al, 2013) | ND |
| RHCBG99 luciferase T. gondii parasite | ~700 nM (Dogga et al, 2017) | ~500 nM | > 10 μM (Dogga et al, 2017) | ~300 nM (Dogga et al, 2017) |
| Ku80Luc T. gondii parasite | ~700 nM | ND | > 10 μM | ~300 nM |
| Ku80LucASP3/F386Y T. gondii parasite | 2.1 μM | ND | > 10 μM | ~300 nM |
| ASP3ty IP | ~6 nM | ND | > 1 μM | ND |
| ASP3tyF344Y IP | ~50 nM | ND | > 1 μM | ND |
| ASP3tyF386Y IP | ~50 nM | ND | > 1 μM | ND |
| ASP3tyF344C IP | ~40 nM | ND | > 1 μM | ND |
| r‐PfPMIX WT | ~650 nM | ND | > 1 μM | ND |
| r‐PfPMIXF291Y | ~1 μM | ND | > 1 μM | ND |
| r‐PfPMX WT | ~3 nM | ND | > 1 μM | ND |
| r‐PfPMXF305Y | ~45 nM | ND | > 1 μM | ND |
Table comparing IC50 values previously reported elsewhere or reported 1st time in this work. ND, not determined.