Table V.
Pathways associated with the differential proteins in metformin-treated rat livers, as determined by KEGG analysis.
| No. | Pathway ID | KEGG pathway | P-value |
|---|---|---|---|
| 1 | ko00830 | Retinol metabolism | <0.00001 |
| 2 | ko00140 | Steroid hormone biosynthesis | <0.00001 |
| 3 | ko00983 | Drug metabolism-other enzymes | <0.00001 |
| 4 | ko04976 | Bile secretion | <0.00001 |
| 5 | ko01100 | Metabolic pathways | <0.0001 |
| 6 | ko00980 | Linoleic acid metabolism | <0.001 |
| 7 | ko00982 | Arachidonic acid metabolism | <0.001 |
| 8 | ko00590 | Drug metabolism-cytochrome P450 | <0.001 |
| 9 | ko00591 | Metabolism of xenobiotics by cytochrome P450 | <0.001 |
| 10 | ko03320 | PPAR signaling pathway | <0.001 |
KEGG, Kyoto Encyclopedia of Genes and Genomes.