Fig. 4.

GDP-fucose binding and conservation analysis. (A) Surface representation showing GDP-fucose bound at the cleft between N- and C-terminal lobes (dark and light green, respectively). Residues at the contact interface with GDP-fucose are colored slate blue. GDP-fucose is in CPK colors, with carbon atoms colored magenta. (B) Conservation analysis. The structure of the enzyme is shown in surface representation, colored on a sliding scale from maroon (most conserved) to teal (least conserved) using the program ConSurf (Ashkenazy et al. 2016). The GDP-fucose is shown in CPK colors, with the carbon atoms colored green. This figure is available in black and white in print and in color at Glycobiology online.