Table 1.

Demographic and baseline characteristics.

Variable	N
Age [years], mean ± SD	461	41.8 ± 13.8
Male, n [%]	461	255 [55.3]
White, n [%]	461	447 [97.0]
UC duration [years], mean ± SD	459	7.3 ± 7.0
Prior TNF antagonist use, n [%]	463	72 [15.6]
UC-related concomitant medications,an [%]
Mesalazine	463	304 [65.7]
Azathioprine	463	168 [36.3]
Prednisolone	463	122 [26.3]
Prednisone	463	91 [19.7]
Methylprednisone	463	70 [15.1]
Sulphasalazine	463	36 [7.8]
Mercaptopurine	463	28 [6.0]
Physician’s Global Assessment [PGA], n [%]	460
PGA of 2		386 [83.9]
PGA of 3		74 [16.1]
SCCAI, mean ± SD	461	7.7 ± 2.4
SIBDQ total score, mean ± SD	460	30.9 ± 8.7
Bowel	461	9.5 ± 3.1
Social	460	6.0 ± 2.5
Systemic	461	6.5 ± 2.4
Emotional	461	8.9 ± 3.1
EQ-5D-5L total score, mean ± SD	454	0.6 ± 0.2
EQ-5D-5L VAS, mean ± SD	451	50.9 ± 19.4
TSQM, mean ± SD
Effectiveness	452	35.2 ± 18.5
Side effects	449	70.3 ± 34.3
Convenience	451	68.3 ± 20.4
Global satisfaction	449	38.0 ± 20.5
WPAI, mean ± SD
Work time missed [%]b	223	20.4 ± 30.1
Impairment while working [%]b	229	50.2 ± 24.8
Overall work impairment [%]b	221	58.5 ± 26.7
Activity impairment [%]	446	59.0 ± 23.5

EQ-5D-5L, The European Quality of Life—5 Dimensions—5 Level; PGA, Physician’s Global Assessment; SCCAI, Simple Clinical Colitis Activity Index; SD, standard deviation; SIBDQ, Short Inflammatory Bowel Disease Questionnaire TNF, tumour necrosis factor; TSQM, Treatment Satisfaction Questionnaire for Medication; UC, ulcerative colitis; VAS, visual analogue scale; WPAI, Work Productivity and Activity Impairment.

^aConcomitant UC-related medications administered to ≥ 5% of patients. A concomitant medication was defined as any medication that started before the first dose of adalimumab [ADA] and continued after the first dose of study drug or any medication that started on or after the first dose of ADA, but was not started later than 14 days after the last dose of ADA.

^bOnly patients who were employed were assessed.