Table 3.

List of genes assessed by RT-PCR in UC patients [Table 1, Group 2]. For each target gene, comparisons between inactive [endoscopic Mayo score = 0; n = 25] and active [endoscopic Mayo score ≥ 1; n = 86] UC patients using the Wilcoxon test, the correlation of the transcriptional profile and the endoscopic activity [endoscopic Mayo score and MS] using the Spearman rank correlation coefficient, and the pairwise analysis of endoscopic Mayo score using an adjusted Wilcoxon test for multiple comparisons was carried out. The p-value or Benjamini-Hochberg adjusted p-value [FDR] and the mean fold-change [Fch] are shown for each comparison. The p-value and rho value are shown for the Spearman correlation.

	Wilcoxon		Spearman correlation		Pairwise analysis						Spearman correlation
	Active vs inactive		Endoscopic Mayo score		Score 1 vs 0		Score 2 vs 0		Score 3 vs 0		MS
Gene	p-Value	Fch	P-value	rho	FDR	Fch	FDR	Fch	FDR	Fch	p-Value	rho
HP	0.000	2.656	0.000	0.471	0.105	1.633	0.026	1.894	0.000	4.246	0.000	0.465
CD177	0.001	5.825	0.000	0.370	0.120	3.000	0.043	4.091	0.001	10.294	0.001	0.338
GPR84	0.001	1.973	0.000	0.393	0.119	1.276	0.025	1.507	0.002	2.925	0.000	0.362
CST7	0.005	1.518	0.001	0.321	0.199	1.249	0.192	1.280	0.007	1.842	0.002	0.319
S100A12	0.017	1.877	0.001	0.309	0.423	1.250	0.101	1.724	0.026	2.493	0.022	0.243
ARG1	0.036	1.507	0.001	0.302	0.796	1.155	0.366	1.219	0.016	1.963	0.124	0.160
ANXA3	0.037	1.811	0.001	0.336	0.533	1.263	0.210	1.482	0.029	2.582	0.005	0.318
ANKRD22	0.048	1.637	0.005	0.280	0.980	1.032	0.108	1.526	0.088	2.108	0.041	0.221
ZDHHC19	0.050	1.879	0.002	0.293	0.627	1.183	0.520	1.305	0.035	2.918	0.019	0.244
HK3	0.054	1.289	0.001	0.313	0.929	1.042	0.537	1.125	0.017	1.564	0.016	0.247
GALNT14	0.057	1.589	0.000	0.360	0.939	1.063	0.630	1.214	0.006	2.278	0.009	0.276
CARD16	0.075	1.180	0.001	0.315	0.976	-1.033	0.581	1.087	0.017	1.383	0.005	0.285
CASP5	0.081	1.263	0.050	0.187	0.440	1.205	0.440	1.194	0.440	1.338	0.033	0.220
AIM2	0.105	1.274	0.002	0.318	0.948	-1.147	0.659	1.116	0.027	1.651	0.015	0.271
TLR5	0.144	1.314	0.007	0.255	0.806	-1.001	0.533	1.248	0.082	1.573	0.039	0.213
MMP9	0.147	1.448	0.008	0.252	0.759	1.053	0.421	1.182	0.116	1.927	0.042	0.209
CA4	0.161	1.261	0.028	0.209	0.874	1.113	0.874	1.054	0.224	1.487	0.322	0.103
C1QB	0.254	1.214	0.263	0.108	0.814	1.048	0.586	1.349	0.586	1.254	0.028	0.227
CLEC4D	0.364	1.224	0.001	0.299	0.126	-1.244	0.358	1.163	0.046	1.606	0.019	0.240
FBXO6	0.456	1.135	0.032	0.203	0.831	-1.022	0.831	-1.035	0.157	1.343	0.051	0.201
SLC26A8	0.465	1.168	0.011	0.241	0.327	-1.236	0.948	1.050	0.095	1.530	0.035	0.216
TDRD9	0.659	1.238	0.030	0.206	0.623	-1.064	0.329	-1.081	0.088	1.690	0.268	0.115
CD274	0.964	1.109	0.248	0.114	0.503	-1.236	0.919	1.086	0.594	1.318	0.147	0.154

UC, ulcerative colitis; RT-PCR, real-time polymerase chain reaction; MS, Modified Score.