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. 2017 May 2;11(9):1113–1123. doi: 10.1093/ecco-jcc/jjx058

Figure 4.

Figure 4.

NTPDase2-deficient mice exhibit pro-inflammatory macrophage phenotype in dextran sodium sulphate [DSS]-induced colitis. A. Gating strategy of macrophages after isolation from colon tissue. After gating of live, single cells [not shown], CD45+CD11b+F4/80+ cells were gated as shown and defined as macrophages [Gate ‘N’]. Exemplary gating for MHCII positivity. B. Comparison of macrophage markers [in % of CD45+CD11b+F4/80+ cells as shown in A] between wild type [WT] and Entpd2 null mice [n = 5 per group]. Error bars show standard deviation; p-values are calculated using Student’s t test [*p < 0.05, **p < 0.005, ***p < 0.001].